Identification of Phenylpyrazolone Dimers as a New Class of Anti‐Trypanosoma cruzi Agents

Chagas disease is becoming a worldwide problem; it is currently estimated that over six million people are infected. The two drugs in current use, benznidazole and nifurtimox, require long treatment regimens, show limited efficacy in the chronic phase of infection, and are known to cause adverse eff...

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Publicado en:ChemMedChem
Autores principales: Sijm, Maarten, Siciliano de Araújo, Julianna, Ramos Llorca, Alba, Orrling, Kristina, Stiny, Lydia, Matheeussen, An, Maes, Louis, de Esch, Iwan J. P., de Nazaré Correia Soeiro, Maria, Sterk, Geert Jan, Leurs, Rob
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771560/
https://ncbi.nlm.nih.gov/pubmed/31319019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201900370
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