Identification of Phenylpyrazolone Dimers as a New Class of Anti‐Trypanosoma cruzi Agents

Chagas disease is becoming a worldwide problem; it is currently estimated that over six million people are infected. The two drugs in current use, benznidazole and nifurtimox, require long treatment regimens, show limited efficacy in the chronic phase of infection, and are known to cause adverse eff...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ChemMedChem
Prif Awduron: Sijm, Maarten, Siciliano de Araújo, Julianna, Ramos Llorca, Alba, Orrling, Kristina, Stiny, Lydia, Matheeussen, An, Maes, Louis, de Esch, Iwan J. P., de Nazaré Correia Soeiro, Maria, Sterk, Geert Jan, Leurs, Rob
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2019
Pynciau:
Full Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771560/
https://ncbi.nlm.nih.gov/pubmed/31319019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201900370
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