Recovering gene interactions from single-cell data using data diffusion

Single-cell RNA-sequencing technologies suffer from many sources of technical noise, including under-sampling of mRNA molecules, often termed ‘dropout’, which can severely obscure important gene-gene relationships. To address this, we developed MAGIC (Markov Affinity-based Graph Imputation of Cells)...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cell
Hlavní autoři: van Dijk, David, Sharma, Roshan, Nainys, Juozas, Yim, Kristina, Kathail, Pooja, Carr, Ambrose, Burdziak, Cassandra, Moon, Kevin R., Chaffer, Christine L., Pattabiraman, Diwakar, Bierie, Brian, Mazutis, Linas, Wolf, Guy, Krishnaswamy, Smita, Pe’er, Dana
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771278/
https://ncbi.nlm.nih.gov/pubmed/29961576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.05.061
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky