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Characterization of cell fate probabilities in single-cell data with Palantir

Single-cell RNA sequencing (scRNA-seq) studies of differentiating systems have raised fundamental questions regarding the discrete versus continuous nature of both differentiation and cell fate. Here we present Palantir, an algorithm that models trajectories of differentiating cells—treating cell fa...

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Bibliografiska uppgifter
I publikationen:Nat Biotechnol
Huvudupphovsmän: Setty, Manu, Kiseliovas, Vaidotas, Levine, Jacob, Gayoso, Adam, Mazutis, Linas, Pe’er, Dana
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549125/
https://ncbi.nlm.nih.gov/pubmed/30899105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-019-0068-4
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