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Characterization of cell fate probabilities in single-cell data with Palantir

Single-cell RNA sequencing (scRNA-seq) studies of differentiating systems have raised fundamental questions regarding the discrete versus continuous nature of both differentiation and cell fate. Here we present Palantir, an algorithm that models trajectories of differentiating cells—treating cell fa...

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Sonraí Bibleagrafaíochta
Foilsithe in:Nat Biotechnol
Main Authors: Setty, Manu, Kiseliovas, Vaidotas, Levine, Jacob, Gayoso, Adam, Mazutis, Linas, Pe’er, Dana
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549125/
https://ncbi.nlm.nih.gov/pubmed/30899105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-019-0068-4
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