Wishbone identifies bifurcating developmental trajectories from single-cell data

Recent single-cell analysis technologies offer an unprecedented opportunity to elucidate developmental pathways. Here we present Wishbone, an algorithm for positioning single cells along bifurcating developmental trajectories with high resolution. Wishbone uses multi-dimensional single-cell data, su...

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Gepubliceerd in:Nat Biotechnol
Hoofdauteurs: Setty, Manu, Tadmor, Michelle D, Reich-Zeliger, Shlomit, Angel, Omer, Salame, Tomer Meir, Kathail, Pooja, Choi, Kristy, Bendall, Sean, Friedman, Nir, Pe’er, Dana
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900897/
https://ncbi.nlm.nih.gov/pubmed/27136076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3569
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