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Dirichlet Process Mixture Model for Correcting Technical Variation in Single-Cell Gene Expression Data

We introduce an iterative normalization and clustering method for single-cell gene expression data. The emerging technology of single-cell RNA-seq gives access to gene expression measurements for thousands of cells, allowing discovery and characterization of cell types. However, the data is confound...

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Detalhes bibliográficos
Publicado no:JMLR Workshop Conf Proc
Main Authors: Prabhakaran, Sandhya, Azizi, Elham, Carr, Ambrose, Pe’er, Dana
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004614/
https://ncbi.nlm.nih.gov/pubmed/29928470
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