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Ahi1 promotes Arl13b ciliary recruitment, regulates Arl13b stability and is required for normal cell migration
Mutations in the Abelson-helper integration site 1 (AHI1) gene are associated with neurological/neuropsychiatric disorders, and cause the neurodevelopmental ciliopathy Joubert syndrome (JBTS). Here, we show that deletion of the transition zone (TZ) protein Ahi1 in mouse embryonic fibroblasts (MEFs)...
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| Published in: | J Cell Sci |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Company of Biologists Ltd
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6771145/ https://ncbi.nlm.nih.gov/pubmed/31391239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.230680 |
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