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Palmitoylation of the ciliary GTPase ARL13b is necessary for its stability and its role in cilia formation

Primary cilia are hairlike extensions of the plasma membrane of most mammalian cells that serve specialized signaling functions. To traffic properly to cilia, multiple cilia proteins rely on palmitoylation, the post-translational attachment of a saturated 16-carbon lipid. However, details regarding...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Roy, Kasturi, Jerman, Stephanie, Jozsef, Levente, McNamara, Thomas, Onyekaba, Ginikanwa, Sun, Zhaoxia, Marin, Ethan P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663873/
https://ncbi.nlm.nih.gov/pubmed/28848045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.792937
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