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The Transition Zone Protein AHI1 Regulates Neuronal Ciliary Trafficking of MCHR1 and Its Downstream Signaling Pathway

The Abelson-helper integration site 1 (AHI1) gene encodes for a ciliary transition zone localizing protein that when mutated causes the human ciliopathy, Joubert syndrome. We prepared and examined neuronal cultures derived from male and female embryonic Ahi1(+/+) and Ahi1(–/–) mice (littermates) and...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Hsiao, Yi-Chun, Muñoz-Estrada, Jesús, Tuz, Karina, Ferland, Russell J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8084322/
https://ncbi.nlm.nih.gov/pubmed/33741721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2993-20.2021
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