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Ahi1, whose human ortholog is mutated in Joubert syndrome, is required for Rab8a localization, ciliogenesis and vesicle trafficking

The primary non-motile cilium, a membrane-ensheathed, microtubule-bundled organelle, extends from virtually all cells and is important for development. Normal functioning of the cilium requires proper axoneme assembly, membrane biogenesis and ciliary protein localization, in tight coordination with...

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Detalhes bibliográficos
Main Authors: Hsiao, Yi-Chun, Tong, Zachary J., Westfall, Jennifer E., Ault, Jeffrey G., Page-McCaw, Patrick S., Ferland, Russell J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748898/
https://ncbi.nlm.nih.gov/pubmed/19625297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp335
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