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Ahi1, whose human ortholog is mutated in Joubert syndrome, is required for Rab8a localization, ciliogenesis and vesicle trafficking

The primary non-motile cilium, a membrane-ensheathed, microtubule-bundled organelle, extends from virtually all cells and is important for development. Normal functioning of the cilium requires proper axoneme assembly, membrane biogenesis and ciliary protein localization, in tight coordination with...

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Главные авторы: Hsiao, Yi-Chun, Tong, Zachary J., Westfall, Jennifer E., Ault, Jeffrey G., Page-McCaw, Patrick S., Ferland, Russell J.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748898/
https://ncbi.nlm.nih.gov/pubmed/19625297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp335
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