Retinal Degeneration and Failure of Photoreceptor Outer Segment Formation in Mice with Targeted Deletion of the Joubert Syndrome Gene, Ahi1

Vertebrate photoreceptors have a modified cilium composed of a basal body, axoneme and outer segment. The outer segment includes stacked membrane discs, containing opsin and the signal transduction apparatus mediating phototransduction. In photoreceptors, two distinct classes of vesicles are traffic...

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Detalhes bibliográficos
Main Authors: Westfall, Jennifer E., Hoyt, Carlton, Liu, Qin, Hsiao, Yi-Chun, Pierce, Eric A., Page-McCaw, Patrick S., Ferland, Russell J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923804/
https://ncbi.nlm.nih.gov/pubmed/20592197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5229-09.2010
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