AT2 Receptor Mediated Activation of the Tyrosine Phosphatase PTP1B Blocks Caveolin-1 Enhanced Migration, Invasion and Metastasis of Cancer Cells

The renin–angiotensin receptor AT2R controls systemic blood pressure and is also suggested to modulate metastasis of cancer cells. However, in the latter case, the mechanisms involved downstream of AT2R remain to be defined. We recently described a novel Caveolin-1(CAV1)/Ras-related protein 5A (Rab5...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Martínez-Meza, Samuel, Díaz, Jorge, Sandoval-Bórquez, Alejandra, Valenzuela-Valderrama, Manuel, Díaz-Valdivia, Natalia, Rojas-Celis, Victoria, Contreras, Pamela, Huilcaman, Ricardo, Ocaranza, María Paz, Chiong, Mario, Leyton, Lisette, Lavandero, Sergio, Quest, Andrew F.G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770525/
https://ncbi.nlm.nih.gov/pubmed/31484460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11091299
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