AT2 Receptor Mediated Activation of the Tyrosine Phosphatase PTP1B Blocks Caveolin-1 Enhanced Migration, Invasion and Metastasis of Cancer Cells

The renin–angiotensin receptor AT2R controls systemic blood pressure and is also suggested to modulate metastasis of cancer cells. However, in the latter case, the mechanisms involved downstream of AT2R remain to be defined. We recently described a novel Caveolin-1(CAV1)/Ras-related protein 5A (Rab5...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Martínez-Meza, Samuel, Díaz, Jorge, Sandoval-Bórquez, Alejandra, Valenzuela-Valderrama, Manuel, Díaz-Valdivia, Natalia, Rojas-Celis, Victoria, Contreras, Pamela, Huilcaman, Ricardo, Ocaranza, María Paz, Chiong, Mario, Leyton, Lisette, Lavandero, Sergio, Quest, Andrew F.G.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770525/
https://ncbi.nlm.nih.gov/pubmed/31484460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11091299
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