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Molecular Modeling Studies on the Binding Mode of the PD-1/PD-L1 Complex Inhibitors

The programmed cell death protein 1 (PD-1)/programmed cell death ligand 1 (PD-L1) is an immune checkpoint (ICP) overexpressed in various types of tumors; thus, it has been considered as an important target for cancer therapy. To determine important residues for ligand binding, we applied molecular d...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Almahmoud, Suliman, Zhong, Haizhen A.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770281/
https://ncbi.nlm.nih.gov/pubmed/31546905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20184654
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