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PD-1/PD-L1 inhibitors
Tumors may adopt normal physiologic checkpoints for immunomodulation leading to an imbalance between tumor growth and host surveillance. Antibodies targeting the PD-1/PD-L1 checkpoint have shown dynamic and durable tumor regressions, suggesting a rebalancing of the host-tumor interaction. Nivolumab...
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| Publicado no: | Curr Opin Pharmacol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4516625/ https://ncbi.nlm.nih.gov/pubmed/26047524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2015.05.011 |
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