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PD-1/PD-L1 inhibitors

Tumors may adopt normal physiologic checkpoints for immunomodulation leading to an imbalance between tumor growth and host surveillance. Antibodies targeting the PD-1/PD-L1 checkpoint have shown dynamic and durable tumor regressions, suggesting a rebalancing of the host-tumor interaction. Nivolumab...

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Sonraí Bibleagrafaíochta
Foilsithe in:Curr Opin Pharmacol
Main Authors: Sunshine, Joel, Taube, Janis M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516625/
https://ncbi.nlm.nih.gov/pubmed/26047524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2015.05.011
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