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Conformational Studies of Glucose Transporter 1 (GLUT1) as an Anticancer Drug Target

Glucose transporter 1 (GLUT1) is a facilitative glucose transporter overexpressed in various types of tumors; thus, it has been considered as an important target for cancer therapy. GLUT1 works through conformational switching from an outward-open (OOP) to an inward-open (IOP) conformation passing t...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Almahmoud, Suliman, Wang, Xiaofang, Vennerstrom, Jonathan L., Zhong, Haizhen A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600248/
https://ncbi.nlm.nih.gov/pubmed/31181707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24112159
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