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ABT-737 Triggers Caspase-Dependent Inhibition of Platelet Procoagulant Extracellular Vesicle Release during Apoptosis and Secondary Necrosis In Vitro

Platelet lifespan is limited by activation of intrinsic apoptosis. Apoptotic platelets are rapidly cleared from the circulation in vivo. ABT-737 triggers platelet apoptosis and is a useful tool for studying this process. However, in vitro experiments lack clearance mechanisms for apoptotic platelets...

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Detalhes bibliográficos
Publicado no:Thromb Haemost
Main Authors: Wei, Hao, Harper, Matthew T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768798/
https://ncbi.nlm.nih.gov/pubmed/31493778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0039-1693694
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