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P2Y12 antagonist ticagrelor inhibits the release of procoagulant extracellular vesicles from activated platelets

BACKGROUND: Activated platelets release platelet extracellular vesicles (PEVs). Adenosine diphosphate (ADP) receptors P2Y1 and P2Y12 both play a role in platelet activation, The present hypothesis herein is that the inhibition of these receptors may affect the release of PEVs. METHODS: Platelet-rich...

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Detalhes bibliográficos
Publicado no:Cardiol J
Main Authors: Gasecka, Aleksandra, Nieuwland, Rienk, van der Pol, Edwin, Hajji, Najat, Cwiek, Agata, Pluta, Kinga, Konwerski, Michał, Filipiak, Krzysztof J.
Formato: Artigo
Idioma:Inglês
Publicado em: Via Medica 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8083044/
https://ncbi.nlm.nih.gov/pubmed/29671861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5603/CJ.a2018.0045
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