Characterization of procoagulant extracellular vesicles and platelet membrane disintegration in DMSO-cryopreserved platelets

BACKGROUND: Freezing is promising for extended platelet (PLT) storage for transfusion. 6% DMSO cryopreserved PLTs (CPPs) are currently in clinical development. CPPs contain significant amount of platelet membrane vesicles (PMVs). PLT-membrane changes and PMV release in CPP are poorly understood, and...

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Dettagli Bibliografici
Pubblicato in:J Extracell Vesicles
Autori principali: Tegegn, Tseday Z., De Paoli, Silvia H., Orecna, Martina, Elhelu, Oumsalama K., Woodle, Samuel A., Tarandovskiy, Ivan D., Ovanesov, Mikhail V., Simak, Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Co-Action Publishing 2016
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Original Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858502/
https://ncbi.nlm.nih.gov/pubmed/27151397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3402/jev.v5.30422
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