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Clinical-grade cryopreserved doxorubicin-loaded platelets: role of cancer cells and platelet extracellular vesicles activation loop

BACKGROUND: Human platelets (PLT) and PLT-extracellular vesicles (PEV) released upon thrombin activation express receptors that interact with tumour cells and, thus, can serve as a delivery platform of anti-cancer agents. Drug-loaded nanoparticles coated with PLT membranes were demonstrated to have...

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Bibliografische gegevens
Gepubliceerd in:J Biomed Sci
Hoofdauteurs: Wu, Yu-Wen, Huang, Cheng-Chain, Changou, Chun Austin, Lu, Long-Sheng, Goubran, Hadi, Burnouf, Thierry
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7087392/
https://ncbi.nlm.nih.gov/pubmed/32200762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-020-00633-2
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