Inhibition of integrin α(D)β(2)–mediated macrophage adhesion to end product of docosahexaenoic acid (DHA) oxidation prevents macrophage accumulation during inflammation

A critical step in the development of chronic inflammatory diseases is the accumulation of proinflammatory macrophages in the extracellular matrix (ECM) of peripheral tissues. The adhesion receptor integrin α(D)β(2) promotes the development of atherosclerosis and diabetes by supporting macrophage re...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Cui, Kui, Podolnikova, Nataly P., Bailey, William, Szmuc, Eric, Podrez, Eugene A., Byzova, Tatiana V., Yakubenko, Valentin P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768641/
https://ncbi.nlm.nih.gov/pubmed/31395659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009590
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