Molecular underpinnings of integrin binding to collagen-mimetic peptides containing vascular Ehlers–Danlos syndrome–associated substitutions

Collagens carry out critical extracellular matrix (ECM) functions by interacting with numerous cell receptors and ECM components. Single glycine substitutions in collagen III, which predominates in vascular walls, result in vascular Ehlers–Danlos syndrome (vEDS), leading to arterial, uterine, and in...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Hoop, Cody L., Kemraj, Allysa P., Wang, Baifan, Gahlawat, Sonal, Godesky, Madison, Zhu, Jie, Warren, Haley R., Case, David A., Shreiber, David I., Baum, Jean
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2019
Onderwerpen:
Glycobiology and Extracellular Matrices
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768638/
https://ncbi.nlm.nih.gov/pubmed/31406019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009685
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