Molecular underpinnings of integrin binding to collagen-mimetic peptides containing vascular Ehlers–Danlos syndrome–associated substitutions

Collagens carry out critical extracellular matrix (ECM) functions by interacting with numerous cell receptors and ECM components. Single glycine substitutions in collagen III, which predominates in vascular walls, result in vascular Ehlers–Danlos syndrome (vEDS), leading to arterial, uterine, and in...

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Vydáno v:J Biol Chem
Hlavní autoři: Hoop, Cody L., Kemraj, Allysa P., Wang, Baifan, Gahlawat, Sonal, Godesky, Madison, Zhu, Jie, Warren, Haley R., Case, David A., Shreiber, David I., Baum, Jean
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
Glycobiology and Extracellular Matrices
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768638/
https://ncbi.nlm.nih.gov/pubmed/31406019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009685
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