Molecular underpinnings of integrin binding to collagen-mimetic peptides containing vascular Ehlers–Danlos syndrome–associated substitutions

Collagens carry out critical extracellular matrix (ECM) functions by interacting with numerous cell receptors and ECM components. Single glycine substitutions in collagen III, which predominates in vascular walls, result in vascular Ehlers–Danlos syndrome (vEDS), leading to arterial, uterine, and in...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Hoop, Cody L., Kemraj, Allysa P., Wang, Baifan, Gahlawat, Sonal, Godesky, Madison, Zhu, Jie, Warren, Haley R., Case, David A., Shreiber, David I., Baum, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768638/
https://ncbi.nlm.nih.gov/pubmed/31406019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009685
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