Molecular underpinnings of integrin binding to collagen-mimetic peptides containing vascular Ehlers–Danlos syndrome–associated substitutions

Collagens carry out critical extracellular matrix (ECM) functions by interacting with numerous cell receptors and ECM components. Single glycine substitutions in collagen III, which predominates in vascular walls, result in vascular Ehlers–Danlos syndrome (vEDS), leading to arterial, uterine, and in...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Hoop, Cody L., Kemraj, Allysa P., Wang, Baifan, Gahlawat, Sonal, Godesky, Madison, Zhu, Jie, Warren, Haley R., Case, David A., Shreiber, David I., Baum, Jean
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2019
Soggetti:
Glycobiology and Extracellular Matrices
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768638/
https://ncbi.nlm.nih.gov/pubmed/31406019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009685
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