Molecular underpinnings of integrin binding to collagen-mimetic peptides containing vascular Ehlers–Danlos syndrome–associated substitutions

Collagens carry out critical extracellular matrix (ECM) functions by interacting with numerous cell receptors and ECM components. Single glycine substitutions in collagen III, which predominates in vascular walls, result in vascular Ehlers–Danlos syndrome (vEDS), leading to arterial, uterine, and in...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Hoop, Cody L., Kemraj, Allysa P., Wang, Baifan, Gahlawat, Sonal, Godesky, Madison, Zhu, Jie, Warren, Haley R., Case, David A., Shreiber, David I., Baum, Jean
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2019
Fag:
Glycobiology and Extracellular Matrices
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768638/
https://ncbi.nlm.nih.gov/pubmed/31406019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009685
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