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Role of the active zone protein, ELKS, in insulin secretion from pancreatic β-cells
BACKGROUND: Insulin is stored within large dense-core granules in pancreatic beta (β)-cells and is released by Ca(2+)-triggered exocytosis with increasing blood glucose levels. Polarized and targeted secretion of insulin from β-cells in pancreatic islets into the vasculature has been proposed; howev...
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| Udgivet i: | Mol Metab |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6768504/ https://ncbi.nlm.nih.gov/pubmed/31500835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.06.017 |
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