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Children and adolescents with sickle cell disease have worse cold and mechanical hypersensitivity during acute painful events

Sickle cell disease (SCD) pain associates with cold temperature and touch. Patients and murine models with SCD have baseline thermal and mechanical pain. In SCD mice, the baseline hypersensitivity is exacerbated by experimental vaso-occlusive crises. We hypothesized that SCD patients will similarly...

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Detalhes bibliográficos
Publicado no:Pain
Main Authors: Brandow, Amanda M., Hansen, Karla, Nugent, Melodee, Pan, Amy, Panepinto, Julie A, Stucky, Cheryl L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768435/
https://ncbi.nlm.nih.gov/pubmed/30247266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000001407
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