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Children and adolescents with sickle cell disease have worse cold and mechanical hypersensitivity during acute painful events

Sickle cell disease (SCD) pain associates with cold temperature and touch. Patients and murine models with SCD have baseline thermal and mechanical pain. In SCD mice, the baseline hypersensitivity is exacerbated by experimental vaso-occlusive crises. We hypothesized that SCD patients will similarly...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Pain
Päätekijät: Brandow, Amanda M., Hansen, Karla, Nugent, Melodee, Pan, Amy, Panepinto, Julie A, Stucky, Cheryl L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768435/
https://ncbi.nlm.nih.gov/pubmed/30247266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000001407
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