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Children and adolescents with sickle cell disease have worse cold and mechanical hypersensitivity during acute painful events
Sickle cell disease (SCD) pain associates with cold temperature and touch. Patients and murine models with SCD have baseline thermal and mechanical pain. In SCD mice, the baseline hypersensitivity is exacerbated by experimental vaso-occlusive crises. We hypothesized that SCD patients will similarly...
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| 出版年: | Pain |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6768435/ https://ncbi.nlm.nih.gov/pubmed/30247266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000001407 |
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