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Structural Insights into the Regulation Mechanism of Small GTPases by GEFs

Small GTPases are key regulators of cellular events, and their dysfunction causes many types of cancer. They serve as molecular switches by cycling between inactive guanosine diphosphate (GDP)-bound and active guanosine triphosphate (GTP)-bound states. GTPases are deactivated by GTPase-activating pr...

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Foilsithe in:Molecules
Main Authors: Toma-Fukai, Sachiko, Shimizu, Toshiyuki
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6767298/
https://ncbi.nlm.nih.gov/pubmed/31514408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24183308
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