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Coevolution of RAC Small GTPases and their Regulators GEF Proteins

RAC proteins are small GTPases involved in important cellular processes in eukaryotes, and their deregulation may contribute to cancer. Activation of RAC proteins is regulated by DOCK and DBL protein families of guanine nucleotide exchange factors (GEFs). Although DOCK and DBL proteins act as GEFs o...

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Detalles Bibliográficos
Publicado en:Evol Bioinform Online
Autor Principal: Jiménez-Sánchez, Alejandro
Formato: Artigo
Idioma:Inglês
Publicado: Libertas Academica 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872645/
https://ncbi.nlm.nih.gov/pubmed/27226705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/EBO.S38031
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