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Coevolution of RAC Small GTPases and their Regulators GEF Proteins

RAC proteins are small GTPases involved in important cellular processes in eukaryotes, and their deregulation may contribute to cancer. Activation of RAC proteins is regulated by DOCK and DBL protein families of guanine nucleotide exchange factors (GEFs). Although DOCK and DBL proteins act as GEFs o...

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Dettagli Bibliografici
Pubblicato in:Evol Bioinform Online
Autore principale: Jiménez-Sánchez, Alejandro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Libertas Academica 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872645/
https://ncbi.nlm.nih.gov/pubmed/27226705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/EBO.S38031
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