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Selectivity through discriminatory induced fit enables switching of NAD(P)H coenzyme specificity in Old Yellow Enzyme ene‐reductases

Most ene‐reductases belong to the Old Yellow Enzyme (OYE) family of flavin‐dependent oxidoreductases. OYEs use nicotinamide coenzymes as hydride donors to catalyze the reduction of alkenes that contain an electron‐withdrawing group. There have been many investigations of the structures and catalytic...

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Bibliografiset tiedot
Julkaisussa:FEBS J
Päätekijät: Iorgu, Andreea I., Hedison, Tobias M., Hay, Sam, Scrutton, Nigel S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6767020/
https://ncbi.nlm.nih.gov/pubmed/31033202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14862
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