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Activation‐Induced Cytidine Deaminase Regulates Fibroblast Growth Factor/Extracellular Signal‐Regulated Kinases Signaling to Achieve the Naïve Pluripotent State During Reprogramming

Induced pluripotent stem cells (iPSCs) derived by in vitro reprogramming of somatic cells retain the capacity to self‐renew and to differentiate into many cell types. Pluripotency encompasses multiple states, with naïve iPSCs considered as ground state, possessing high levels of self‐renewal capacit...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Kumar, Ritu, Evans, Todd
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6766926/
https://ncbi.nlm.nih.gov/pubmed/31021461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3023
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