CHD1L Regulated PARP1‐Driven Pluripotency and Chromatin Remodeling During the Early‐Stage Cell Reprogramming

PARP1 and poly(ADP‐ribosyl)ation (PARylation) have been shown to be essential for the initial steps of cellular reprogramming. However, the mechanism underlying PARP1/PARylation‐regulated activation of pluripotency loci remains undetermined. Here, we demonstrate that CHD1L, a DNA helicase, possesses...

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Vydáno v:Stem Cells
Hlavní autoři: Jiang, Bo‐Hua, Chen, Wei‐Yi, Li, Hsin‐Yang, Chien, Yueh, Chang, Wei‐Chao, Hsieh, Pei‐Chen, Wu, Ping, Chen, Chieh‐Yu, Song, Hui‐Yung, Chien, Chian‐Shiu, Sung, Yen‐Jen, Chiou, Shih‐Hwa
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2015
Témata:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832376/
https://ncbi.nlm.nih.gov/pubmed/26201266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2116
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