CHD1L Regulated PARP1‐Driven Pluripotency and Chromatin Remodeling During the Early‐Stage Cell Reprogramming

PARP1 and poly(ADP‐ribosyl)ation (PARylation) have been shown to be essential for the initial steps of cellular reprogramming. However, the mechanism underlying PARP1/PARylation‐regulated activation of pluripotency loci remains undetermined. Here, we demonstrate that CHD1L, a DNA helicase, possesses...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Jiang, Bo‐Hua, Chen, Wei‐Yi, Li, Hsin‐Yang, Chien, Yueh, Chang, Wei‐Chao, Hsieh, Pei‐Chen, Wu, Ping, Chen, Chieh‐Yu, Song, Hui‐Yung, Chien, Chian‐Shiu, Sung, Yen‐Jen, Chiou, Shih‐Hwa
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832376/
https://ncbi.nlm.nih.gov/pubmed/26201266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2116
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