JNK/SAPK Signaling Is Essential for Efficient Reprogramming of Human Fibroblasts to Induced Pluripotent Stem Cells

Reprogramming of somatic cells to the phenotypic state termed “induced pluripotency” is thought to occur through three consecutive stages: initiation, maturation, and stabilisation. The initiation phase is stochastic but nevertheless very important as it sets the gene expression pattern that permits...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Neganova, Irina, Shmeleva, Evgenija, Munkley, Jennifer, Chichagova, Valeria, Anyfantis, George, Anderson, Rhys, Passos, Joao, Elliott, David J., Armstrong, Lyle, Lako, Majlinda
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982072/
https://ncbi.nlm.nih.gov/pubmed/26867034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2327
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