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Human iPSC differentiation to retinal organoids in response to IGF1 and BMP4 activation is line‐ and method‐dependent

Induced pluripotent stem cell (iPSC)‐derived retinal organoids provide a platform to study human retinogenesis, disease modeling, and compound screening. Although retinal organoids may represent tissue structures with greater physiological relevance to the in vivo human retina, their generation is n...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Chichagova, Valeria, Hilgen, Gerrit, Ghareeb, Ali, Georgiou, Maria, Carter, Madeleine, Sernagor, Evelyne, Lako, Majlinda, Armstrong, Lyle
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7383896/
https://ncbi.nlm.nih.gov/pubmed/31721366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3116
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