Human iPSC differentiation to retinal organoids in response to IGF1 and BMP4 activation is line‐ and method‐dependent

Induced pluripotent stem cell (iPSC)‐derived retinal organoids provide a platform to study human retinogenesis, disease modeling, and compound screening. Although retinal organoids may represent tissue structures with greater physiological relevance to the in vivo human retina, their generation is n...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Stem Cells
Main Authors: Chichagova, Valeria, Hilgen, Gerrit, Ghareeb, Ali, Georgiou, Maria, Carter, Madeleine, Sernagor, Evelyne, Lako, Majlinda, Armstrong, Lyle
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Inc. 2019
Teme:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7383896/
https://ncbi.nlm.nih.gov/pubmed/31721366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3116
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