Human iPSC differentiation to retinal organoids in response to IGF1 and BMP4 activation is line‐ and method‐dependent

Induced pluripotent stem cell (iPSC)‐derived retinal organoids provide a platform to study human retinogenesis, disease modeling, and compound screening. Although retinal organoids may represent tissue structures with greater physiological relevance to the in vivo human retina, their generation is n...

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Détails bibliographiques
Publié dans:Stem Cells
Auteurs principaux: Chichagova, Valeria, Hilgen, Gerrit, Ghareeb, Ali, Georgiou, Maria, Carter, Madeleine, Sernagor, Evelyne, Lako, Majlinda, Armstrong, Lyle
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons, Inc. 2019
Sujets:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7383896/
https://ncbi.nlm.nih.gov/pubmed/31721366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3116
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