IGF‐1 Signaling Plays an Important Role in the Formation of Three‐Dimensional Laminated Neural Retina and Other Ocular Structures From Human Embryonic Stem Cells

We and others have previously demonstrated that retinal cells can be derived from human embryonic stem cells (hESCs) and induced pluripotent stem cells under defined culture conditions. While both cell types can give rise to retinal derivatives in the absence of inductive cues, this requires extende...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Mellough, Carla B., Collin, Joseph, Khazim, Mahmoud, White, Kathryn, Sernagor, Evelyne, Steel, David H. W., Lako, Majlinda
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691326/
https://ncbi.nlm.nih.gov/pubmed/25827910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2023
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