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Pharmacokinetics, Safety, and Tolerability of Tezepelumab (AMG 157) in Healthy and Atopic Dermatitis Adult Subjects

Tezepelumab (AMG 157) is a monoclonal antibody that targets thymic stromal lymphopoietin and has shown benefits in treating asthma. We assessed the safety, tolerability, and pharmacokinetics of single‐ascending and multiple‐ascending doses in two randomized, double‐blind, placebo‐controlled phase I...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Ther
Main Authors: Parnes, Jane R., Sullivan, John T., Chen, Li, Dias, Clapton
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6766783/
https://ncbi.nlm.nih.gov/pubmed/30779339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1401
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