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Pharmacokinetics, Safety, and Tolerability of Tezepelumab (AMG 157) in Healthy and Atopic Dermatitis Adult Subjects

Tezepelumab (AMG 157) is a monoclonal antibody that targets thymic stromal lymphopoietin and has shown benefits in treating asthma. We assessed the safety, tolerability, and pharmacokinetics of single‐ascending and multiple‐ascending doses in two randomized, double‐blind, placebo‐controlled phase I...

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Publicat a:Clin Pharmacol Ther
Autors principals: Parnes, Jane R., Sullivan, John T., Chen, Li, Dias, Clapton
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6766783/
https://ncbi.nlm.nih.gov/pubmed/30779339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1401
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