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Effect of Multiple Doses of Omeprazole on the Pharmacokinetics, Safety, and Tolerability of Roxadustat in Healthy Subjects

BACKGROUND AND OBJECTIVES: Roxadustat is an orally active hypoxia-inducible factor prolyl hydroxylase inhibitor for the treatment of anemia in chronic kidney disease. This study investigated the effect of multiple daily oral doses of omeprazole on the pharmacokinetics, safety, and tolerability of a...

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書目詳細資料
發表在:Eur J Drug Metab Pharmacokinet
Main Authors: Groenendaal-van de Meent, Dorien, den Adel, Martin, van Dijk, Jan, Barroso-Fernandez, Begona, El Galta, Rachid, Golor, Georg, Schaddelee, Marloes
格式: Artigo
語言:Inglês
出版: Springer International Publishing 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6244714/
https://ncbi.nlm.nih.gov/pubmed/29752643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13318-018-0480-z
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