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Inhibition of microRNA-141-3p Reduces Hypoxia-Induced Apoptosis in H9c2 Rat Cardiomyocytes by Activating the RP105-Dependent PI3K/AKT Signaling Pathway

BACKGROUND: Oxidative stress in myocardial ischemia results in cardiomyocyte apoptosis. The expression of microRNA-141-3p (miR-141-3p) and the 105 kD toll-like receptor protein (TLR), RP105, have been identified in cardiomyocytes in vitro. This study aimed to investigate the effects of hypoxia in H9...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Qin, Qiaoji, Cui, Liqiang, Zhou, Zhenggang, Zhang, Zhirong, Wang, Yini, Zhou, Changyong
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765341/
https://ncbi.nlm.nih.gov/pubmed/31532760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.916361
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