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Pi3kcb Links Hippo-YAP and PI3K-AKT Signaling Pathways to Promote Cardiomyocyte Proliferation and Survival

RATIONALE: YAP, the nuclear effector of Hippo signaling, regulates cellular growth and survival in multiple organs, including the heart, by interacting with TEAD sequence specific DNA-binding proteins. Recent studies showed that YAP stimulates cardiomyocyte proliferation and survival. However, the d...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Lin, Zhiqiang, Zhou, Pingzhu, von Gise, Alexander, Gu, Fei, Ma, Qing, Chen, Jinghai, Guo, Haidong, van Gorp, Pim R. R., Wang, Da-Zhi, Pu, William T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282610/
https://ncbi.nlm.nih.gov/pubmed/25249570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.304457
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