YAP1, the nuclear target of Hippo signaling, stimulates heart growth through cardiomyocyte proliferation but not hypertrophy

Heart growth is tightly controlled so that the heart reaches a predetermined size. Fetal heart growth occurs through cardiomyocyte proliferation, whereas postnatal heart growth involves primarily physiological cardiomyocyte hypertrophy. The Hippo kinase cascade is an important regulator of organ gro...

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Detalhes bibliográficos
Main Authors: von Gise, Alexander, Lin, Zhiqiang, Schlegelmilch, Karin, Honor, Leah B., Pan, Gina M., Buck, Jessica N., Ma, Qing, Ishiwata, Takahiro, Zhou, Bin, Camargo, Fernando D., Pu, William T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289361/
https://ncbi.nlm.nih.gov/pubmed/22308401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116136109
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