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Nuclear targeting of Akt antagonizes aspects of cardiomyocyte hypertrophy
The serine/threonine kinase Akt regulates cellular survival, proliferation, gene transcription, protein translation, metabolism, and differentiation. Although Akt substrates are found throughout the cell, activated Akt normally accumulates in the nucleus, suggesting that biologically relevant target...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1567678/ https://ncbi.nlm.nih.gov/pubmed/16882732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510138103 |
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