Biliverdin Reductase Mediates Hypoxia-Induced EMT via PI3-Kinase and Akt

Chronic hypoxia in the renal parenchyma is thought to induce epithelial-to-mesenchymal transition (EMT), leading to fibrogenesis and ultimately end-stage renal failure. Biliverdin reductase, recently identified as a serine/threonine/tyrosine kinase that may activate phosphatidylinositol 3-kinase (PI...

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Autors principals: Zeng, Rui, Yao, Ying, Han, Min, Zhao, Xiaoqin, Liu, Xiao-Cheng, Wei, Juncheng, Luo, Yun, Zhang, Juan, Zhou, Jianfeng, Wang, Shixuan, Ma, Ding, Xu, Gang
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2008
Matèries:
Clinical Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396754/
https://ncbi.nlm.nih.gov/pubmed/18184861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2006111194
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