RNA editing alterations define manifestation of prion diseases

Prion diseases are fatal neurodegenerative disorders caused by misfolding of the normal prion protein into an infectious cellular pathogen. Clinically characterized by rapidly progressive dementia and accounting for 85% of human prion disease cases, sporadic Creutzfeldt–Jakob disease (sCJD) is the p...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Kanata, Eirini, Llorens, Franc, Dafou, Dimitra, Dimitriadis, Athanasios, Thüne, Katrin, Xanthopoulos, Konstantinos, Bekas, Nikolaos, Espinosa, Juan Carlos, Schmitz, Matthias, Marín-Moreno, Alba, Capece, Vincenzo, Shormoni, Orr, Andréoletti, Olivier, Bonn, Stefan, Torres, Juan María, Ferrer, Isidre, Zerr, Inga, Sklaviadis, Theodoros
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2019
Témata:
PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765247/
https://ncbi.nlm.nih.gov/pubmed/31492812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1803521116
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