Regional and subtype-dependent miRNA signatures in sporadic Creutzfeldt-Jakob disease are accompanied by alterations in miRNA silencing machinery and biogenesis

Increasing evidence indicates that microRNAs (miRNAs) are contributing factors to neurodegeneration. Alterations in miRNA signatures have been reported in several neurodegenerative dementias, but data in prion diseases are restricted to ex vivo and animal models. The present study identified signifi...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Llorens, Franc, Thüne, Katrin, Martí, Eulàlia, Kanata, Eirini, Dafou, Dimitra, Díaz-Lucena, Daniela, Vivancos, Ana, Shomroni, Orr, Zafar, Saima, Schmitz, Matthias, Michel, Uwe, Fernández-Borges, Natalia, Andréoletti, Olivier, del Río, José Antonio, Díez, Juana, Fischer, Andre, Bonn, Stefan, Sklaviadis, Theodoros, Torres, Juan Maria, Ferrer, Isidre, Zerr, Inga
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794191/
https://ncbi.nlm.nih.gov/pubmed/29357384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006802
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