Regional and subtype-dependent miRNA signatures in sporadic Creutzfeldt-Jakob disease are accompanied by alterations in miRNA silencing machinery and biogenesis

Increasing evidence indicates that microRNAs (miRNAs) are contributing factors to neurodegeneration. Alterations in miRNA signatures have been reported in several neurodegenerative dementias, but data in prion diseases are restricted to ex vivo and animal models. The present study identified signifi...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Llorens, Franc, Thüne, Katrin, Martí, Eulàlia, Kanata, Eirini, Dafou, Dimitra, Díaz-Lucena, Daniela, Vivancos, Ana, Shomroni, Orr, Zafar, Saima, Schmitz, Matthias, Michel, Uwe, Fernández-Borges, Natalia, Andréoletti, Olivier, del Río, José Antonio, Díez, Juana, Fischer, Andre, Bonn, Stefan, Sklaviadis, Theodoros, Torres, Juan Maria, Ferrer, Isidre, Zerr, Inga
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794191/
https://ncbi.nlm.nih.gov/pubmed/29357384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006802
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